Since the game is quite difficult and there doesn't seem to be a guide, I decided to write a quick one - Puzzle Solutions
Subject 264 is a VR horror puzzle game developed by Virtual Guys. I never heard of either but the game was a very nice surprise and I'm thankful I came across it.
You wake up in a room with no memories of your past and all you can hear are creepy sounds. The surroundings are also very creepy. You look around and you don't see a way out. It is up to you now to figure out how to get out of the very first room with 'Subject 264' written in blood on the wall. You will explore your surroundings and interact with different kind of items and you will have to solve your first puzzle. When you do, you will be able to go outside this room and reach another room where you'll have to figure out what to do next. While trying to escape you'll be uncovering your own past and start wondering if what is going on is real or some kind of an experiment or something just in your head.
The game is very atmospheric and I fully immersed in it which also made me tip toe around the rooms and corridors and my immersion was broken only after I ran headfirst into a real life cabinet or table. The feeling of something being totally wrong will stay with you throughout the game making occasional jump scares even more scary.
The puzzles are not particularly easy. While there is logic in them it may not seem like it at first. I went through the first part by trial and error. If you get stuck on a puzzle and you are in the correct room you will hear (your) voice giving you a hint. They are mostly helpful (there was one hint I totally didn't get).
Graphically the game is nicely done, offers different environments to enjoy. There are relatively well preserved rooms like the one you start the game in, ones that are less preserved (the following one) and then ones that are very creepy and scary. Some areas are very dark but you don't need to venture there unless there is a flashlight nearby. In that case there might be some key items in the dark.
Sound is good, there is some tense music and background noise and voices. The voice acting is not bad and it is easy to understand. The sound effects do not break immersion and actually make it better.
The not so good about the game is the fact it was designed for Vive and therefore the controls for Rift are not ideal. It does not seem to like Knuckles either. The game requires 360 degrees tracking and tracking at the floor level since you will be forced to pick up items from the floor and you need to actually grab the objects (can't grab them from distance). There are two types of locomotion - normal joystick one and teleportation - but both are rather slow.
Subject 264 is very atmospheric psychological horror puzzle game that will immerse you in the story and dark past of subject 264. The puzzles are unique, well designed, and not very easy to figure out which makes the game relatively long (5 hours). Graphics and sound are also very well done. There is lot of detail and variety in environments and many objects one can play with which makes the game great for exploration. I'd highly recommend the game to anyone who likes more complex puzzle or escape rooms. Since the game is rather serious, dark and very grave I wouldn't recommend it to people who are struggling with deep depression or unhandled traumas.
Ren (stsungjp on Twitter)